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Dr. Mamelak is moving!

In Accordance with §165.5 of the Texas Administrative Code, Dr. Mamelak is informing all patients that he is leaving Sanova Dermatology. His last day in the clinic will be May 10, 2024.

The public consensus about Accutane (Isotretinoin) is that it is an effective medication for the treatment of moderate to severe acne. Along with its reputation for efficacy, the side effects of this medication also capture people’s attention. In fact, it’s what turns most people off from trying the treatment to begin with. In actuality, it’s an extremely effective medication.

Here is some helpful information for those who have decided to use accutane to treat their severe acne.

What is Accutane?

Accutane is a powerful drug used in the treatment of acne. It’s a naturally occurring derivative of Vitamin A and has been found to be an extremely effective and reliable treatment for severe acne vulgaris. This medicine has also been used to treat rosacea and a number of other skin conditions.

Accutane is the brand name given to the generic drug, isotretinoin. Other brand names include: Absorica, Amnesteem, Claravis, Myorisan, Sotret, and Zenatane.

How does Acccutane work?

Accutane works by shrinking the oil glands in the skin that produce sebum (the naturally occurring oil in the skin). It also works by reducing the amount of P. acnes in oil glands, which are bacteria that live off the sebum and contribute to the development of pimples. In its most basic form, acne is an overgrowth of bacteria in a clogged pore. Because isotretinoin (accutane) affects rapidly dividing cells, it changes the differentiation and  turnover in skin cells. This leads to fewer clogged pores and, thus, decreased acne formation. This medication has also been proven to have the effects of an anti-inflammatory, which decreases swelling and redness caused by acne in the skin.

What dose of Accutane should I be on?

The accurate dosage will depend on the patient’s weight, according to experts. The dosage is increased over time, and the medication is stopped once the patient reaches his or her target. In general, patients begin at dose of 0.5 mg/kg/d for 4 weeks and increased as tolerated until a cumulative dose of 120-150 mg/kg is achieved.

How long do I need to be on Accutane?

The length of treatment will vary from patient to patient, but on average, the treatment time is 4 to 6 months. It is possible that a patient may need to be treated more than once with this medication.

When will I see results?

Some patients begin to see significant improvement within the first month of treatment. Others, however, may not see results until they have been on the medication for months. It depends on the patient and their skin’s tolerance for the drug.

Is Accutane a cure?

A good number of patients, around 70-80%, find that Isotretinoin is the answer to their acne problems. However, there is a small chance that acne can return. If patient experiences breakouts after Accutane, the acne is often much less severe and can be controlled with a wash or a cream. Occasionally, patients may be prescribed an additional round of Accutane if their dermatologist feels that it would be most effective.

If you have more questions about Accutane and acne treatments, contact me!